311d

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[[Image:311d.png|left|200px]]
[[Image:311d.png|left|200px]]
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{{STRUCTURE_311d| PDB=311d | SCENE= }}
{{STRUCTURE_311d| PDB=311d | SCENE= }}
===THE ROLE OF HYDROGEN BONDING IN MINOR-GROOVE DRUG-DNA RECOGNITION. STRUCTURE OF A BIS-AMIDINIUM DERIVATIVE OF HOECHST 33258 COMPLEXED TO THE DODECANUCLEOTIDE D(CGCGAATTCGCG)2===
===THE ROLE OF HYDROGEN BONDING IN MINOR-GROOVE DRUG-DNA RECOGNITION. STRUCTURE OF A BIS-AMIDINIUM DERIVATIVE OF HOECHST 33258 COMPLEXED TO THE DODECANUCLEOTIDE D(CGCGAATTCGCG)2===
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{{ABSTRACT_PUBMED_9162901}}
{{ABSTRACT_PUBMED_9162901}}
==About this Structure==
==About this Structure==
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=311D OCA].
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[[311d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=311D OCA].
==Reference==
==Reference==
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Structure of a bis-amidinium derivative of hoechst 33258 complexed to dodecanucleotide d(CGCGAATTCGCG)2: the role of hydrogen bonding in minor groove drug-DNA recognition., Clark GR, Boykin DW, Czarny A, Neidle S, Nucleic Acids Res. 1997 Apr 15;25(8):1510-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9162901 9162901]
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<ref group="xtra">PMID:009162901</ref><ref group="xtra">PMID:018798655</ref><references group="xtra"/>
[[Category: Boykin, D W.]]
[[Category: Boykin, D W.]]
[[Category: Clark, G R.]]
[[Category: Clark, G R.]]
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[[Category: B-dna]]
[[Category: B-dna]]
[[Category: Complexed with drug]]
[[Category: Complexed with drug]]
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[[Category: Dna]]
[[Category: Double helix]]
[[Category: Double helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 11:36:18 2008''
 

Revision as of 17:54, 14 August 2012

Image:311d.png

Template:STRUCTURE 311d

THE ROLE OF HYDROGEN BONDING IN MINOR-GROOVE DRUG-DNA RECOGNITION. STRUCTURE OF A BIS-AMIDINIUM DERIVATIVE OF HOECHST 33258 COMPLEXED TO THE DODECANUCLEOTIDE D(CGCGAATTCGCG)2

Template:ABSTRACT PUBMED 9162901

About this Structure

311d is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Clark GR, Boykin DW, Czarny A, Neidle S. Structure of a bis-amidinium derivative of hoechst 33258 complexed to dodecanucleotide d(CGCGAATTCGCG)2: the role of hydrogen bonding in minor groove drug-DNA recognition. Nucleic Acids Res. 1997 Apr 15;25(8):1510-5. PMID:9162901
  • Nguyen B, Neidle S, Wilson WD. A role for water molecules in DNA-ligand minor groove recognition. Acc Chem Res. 2009 Jan 20;42(1):11-21. PMID:18798655 doi:10.1021/ar800016q

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OCA

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