G09SecL04Tpc2

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(Outer Surface Protein A (OspA))
(Outer Surface Protein A (OspA))
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<Structure load='1fj1' size='500' frame='true' align='right' caption='Outer Surface Protein A Fab LA-2 Complex' scene='Insert optional scene name here' />
<Structure load='1fj1' size='500' frame='true' align='right' caption='Outer Surface Protein A Fab LA-2 Complex' scene='Insert optional scene name here' />
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Outer surface protein A (OspA) is a major lipoprotein[[lipoprotein]] on the borrelia burgdorferi spirochete which is a causative agent of Lyme Disease. The three loops in the C-terminus define the OspA antigen-antibody complex. The interaction between the loops and the LA-2 (antibody) forms the basis for OspA vaccination. Along with other surface proteins, OspA has many important functions that are associated with Lyme Diseases uch as late stage neurological disorders.
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Outer surface protein A (OspA) is a major [[lipoprotein]] on the borrelia burgdorferi spirochete which is a causative agent of Lyme Disease. The three loops in the C-terminus define the OspA antigen-antibody complex. The interaction between the loops and the LA-2 (antibody) forms the basis for OspA vaccination. Along with other surface proteins, OspA has many important functions that are associated with Lyme Diseases uch as late stage neurological disorders.
== Introduction to Lyme Disease ==
== Introduction to Lyme Disease ==
== Structure ==
== Structure ==

Revision as of 03:36, 16 August 2012

Outer Surface Protein A (OspA)

Outer Surface Protein A Fab LA-2 Complex

Drag the structure with the mouse to rotate

Outer surface protein A (OspA) is a major lipoprotein on the borrelia burgdorferi spirochete which is a causative agent of Lyme Disease. The three loops in the C-terminus define the OspA antigen-antibody complex. The interaction between the loops and the LA-2 (antibody) forms the basis for OspA vaccination. Along with other surface proteins, OspA has many important functions that are associated with Lyme Diseases uch as late stage neurological disorders.

Introduction to Lyme Disease

Structure

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Albert Kurian, Nabil Faridi, Michal Harel, Amar Patole

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