Spermidine Synthase
From Proteopedia
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[[1inl]] - The crystal structure of the PAPT from Thermotoga maritima (TmPAPT) has been solved to 1.5 A resolution. | [[1inl]] - The crystal structure of the PAPT from Thermotoga maritima (TmPAPT) has been solved to 1.5 A resolution. | ||
The structure of TmPAPT in a complex with adoDATO ([[1jq3]]) can also be found on this site. | The structure of TmPAPT in a complex with adoDATO ([[1jq3]]) can also be found on this site. | ||
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| + | ==3D structures of spermidine synthase== | ||
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| + | [[1inl]] – TmSPS – ''Thermotoga maritima''<br /> | ||
| + | [[1mjf]] – SPS – ''Pyrococcus furiosus''<br /> | ||
| + | [[2e5w]], [[2zsu]] - SPS – ''Pyrococcus horikishii''<br /> | ||
| + | [[1iy9]] – SPS – ''Bacillus subtilis''<br /> | ||
| + | [[1xj5]], [[2q41]] – SPS – ''Arabidopsis thaliana''<br /> | ||
| + | [[2b2c]] – SPS – ''Caenorhabditis elegans''<br /> | ||
| + | [[2o05]], [[2o06]], [[2o07]], [[2o0l]] – SPS – human<br /> | ||
| + | [[2cmg]], [[2cmh]] – SPS – ''Helicobacter pylori''<br /> | ||
| + | [[2pss]] – PfSPS – ''Plasmodium falciparum''<br /> | ||
| + | [[3o4f]] – SPS – ''Escherichia coli'' | ||
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| + | Binary complexes of spermidine synthase | ||
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| + | [[1jq3]] – TmSPS + transition state analog<br /> | ||
| + | [[2hte]], [[2pt6]] - PfSPS + methylthioadenosine <br /> | ||
| + | [[2i7c]] - PfSPS + transition state analog<br /> | ||
| + | [[2pwp]] - PfSPS + spermidine<br /> | ||
| + | [[3b7p]] - PfSPS + spermine<br /> | ||
| + | [[3bwc]] - SPS + SAM – ''Trypanosoma cruzi''<br /> | ||
| + | [[3rw9]] - hSPS + SAH | ||
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| + | Ternary complexes of spermidine synthase | ||
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| + | [[3c6k]] - hSPS + methylthioadenosine + spermidine<br /> | ||
| + | [[3c6m]] - hSPS + methylthioadenosine + spermine<br /> | ||
| + | [[2pt6]], [[3rie]] - PfSPS + inhibitor + methylthioadenosine | ||
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Created with the participation of [[User:Lindsey Butler|Lindsey Butler]]. | Created with the participation of [[User:Lindsey Butler|Lindsey Butler]]. | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:34, 16 August 2012
Under construction!
Polyamines are essential in all branches of life. Spermidine synthase (putrescine aminopropyltransferase, PAPT) catalyzes the biosynthesis of spermidine, a ubiquitous polyamine.
1inl - The crystal structure of the PAPT from Thermotoga maritima (TmPAPT) has been solved to 1.5 A resolution.
The structure of TmPAPT in a complex with adoDATO (1jq3) can also be found on this site.
3D structures of spermidine synthase
1inl – TmSPS – Thermotoga maritima
1mjf – SPS – Pyrococcus furiosus
2e5w, 2zsu - SPS – Pyrococcus horikishii
1iy9 – SPS – Bacillus subtilis
1xj5, 2q41 – SPS – Arabidopsis thaliana
2b2c – SPS – Caenorhabditis elegans
2o05, 2o06, 2o07, 2o0l – SPS – human
2cmg, 2cmh – SPS – Helicobacter pylori
2pss – PfSPS – Plasmodium falciparum
3o4f – SPS – Escherichia coli
Binary complexes of spermidine synthase
1jq3 – TmSPS + transition state analog
2hte, 2pt6 - PfSPS + methylthioadenosine
2i7c - PfSPS + transition state analog
2pwp - PfSPS + spermidine
3b7p - PfSPS + spermine
3bwc - SPS + SAM – Trypanosoma cruzi
3rw9 - hSPS + SAH
Ternary complexes of spermidine synthase
3c6k - hSPS + methylthioadenosine + spermidine
3c6m - hSPS + methylthioadenosine + spermine
2pt6, 3rie - PfSPS + inhibitor + methylthioadenosine
Created with the participation of Lindsey Butler.
