3twj

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-	'''Unreleased structure'''	+	[[Image:3twj.jpg|left|200px]]
-	The entry 3twj is ON HOLD until Paper Publication	+	{{STRUCTURE_3twj| PDB=3twj | SCENE= }}
-	Authors: Martin, M.P., Zhu, J.-Y., Schonbrunn, E.	+	===Rho-associated protein kinase 1 (ROCK 1) IN COMPLEX WITH RKI1447===
-	Description: Rho-associated protein kinase 1 (ROCK 1) IN COMPLEX WITH RKI1447	+	{{ABSTRACT_PUBMED_22846914}}
		+
		+	==About this Structure==
		+	[[3twj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TWJ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022846914</ref><references group="xtra"/>
		+	[[Category: Homo sapiens]]
		+	[[Category: Non-specific serine/threonine protein kinase]]
		+	[[Category: Martin, M P.]]
		+	[[Category: Schonbrunn, E.]]
		+	[[Category: Zhu, J Y.]]
		+	[[Category: Dimer]]
		+	[[Category: Dimerization]]
		+	[[Category: Kinase]]
		+	[[Category: Myosin]]
		+	[[Category: Transferase-transferase inhibitor complex]]

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Revision as of 05:52, 22 August 2012

Template:STRUCTURE 3twj

Rho-associated protein kinase 1 (ROCK 1) IN COMPLEX WITH RKI1447

Template:ABSTRACT PUBMED 22846914

About this Structure

3twj is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Patel RA, Forinash KD, Pireddu R, Sun Y, Sun N, Martin MP, Schonbrunn E, Lawrence NJ, Sebti SM. RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and anti-tumor activities in breast cancer. Cancer Res. 2012 Jul 30. PMID:22846914 doi:10.1158/0008-5472.CAN-12-0954