Nuclear receptor

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The structure of the LBD is strongly conserved throughout the familly of nuclear receptors.
The structure of the LBD is strongly conserved throughout the familly of nuclear receptors.
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It is completely folded and composed of a beta-sheet, and 12 alpha-helices arranged in a three layered sandwich.
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It is a globular domain<scene name='Nuclear_receptor/Nr-lbd-/1'>well folded</scene>
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and composed of a beta-sheet, and 12 alpha-helices arranged in a three layered sandwich.
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</StructureSection>
</StructureSection>
<references/>
<references/>

Revision as of 09:02, 6 September 2012

the nuclear receptors facts book [1]

Structure

DBD (DNA Binding Domain)

LBD (Ligand Binding Domain)

Structure of the LBD of a VDR (vitamin D receptor) complexed to 1alpha,25(OH)(2)D(3) and the 20-epi analogs(PDB entry 1ie8)

Drag the structure with the mouse to rotate
  1. Vincent Laudet, Hinrich Gronemeyer, "The nuclear receptor factsbook", Publisher Academic Press, 2002

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Schwarz Benjamin

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