1qmu
From Proteopedia
(New page: 200px<br /> <applet load="1qmu" size="450" color="white" frame="true" align="right" spinBox="true" caption="1qmu, resolution 2.70Å" /> '''DUCK CARBOXYPEPTIDA...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1QMU is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/ | + | 1QMU is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Anas_specularioides Anas specularioides]] with SO4 and ZN as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: ZN. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1QMU OCA]]. |
==Reference== | ==Reference== | ||
Crystal structure of avian carboxypeptidase D domain II: a prototype for the regulatory metallocarboxypeptidase subfamily., Gomis-Ruth FX, Companys V, Qian Y, Fricker LD, Vendrell J, Aviles FX, Coll M, EMBO J. 1999 Nov 1;18(21):5817-26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10545093 10545093] | Crystal structure of avian carboxypeptidase D domain II: a prototype for the regulatory metallocarboxypeptidase subfamily., Gomis-Ruth FX, Companys V, Qian Y, Fricker LD, Vendrell J, Aviles FX, Coll M, EMBO J. 1999 Nov 1;18(21):5817-26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10545093 10545093] | ||
| - | [[Category: | + | [[Category: Anas specularioides]] |
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Aviles, F.X.]] | [[Category: Aviles, F.X.]] | ||
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[[Category: zinc-dependent protease]] | [[Category: zinc-dependent protease]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:27:36 2007'' |
Revision as of 12:22, 30 October 2007
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DUCK CARBOXYPEPTIDASE D DOMAIN II
Overview
The crystal structure of domain II of duck carboxypeptidase D, a, prohormone/propeptide processing enzyme integrated in a three repeat, tandem in the natural system, has been solved, constituting a prototype, for members of the regulatory metallocarboxypeptidase subfamily. It, displays a 300 residue N-terminal alpha/beta-hydrolase subdomain with, overall topological similarity to and general coincidence of the key, catalytic residues with the archetypal pancreatic carboxypeptidase A., However, numerous significant insertions/deletions in segments forming the, funnel-like access to the active site explain differences in specificity, towards larger protein substrates or inhibitors. This alpha/beta-hydrolase, subdomain is followed by a C-terminal 80 residue beta-sandwich subdomain, unique ... [(full description)]
About this Structure
1QMU is a [Single protein] structure of sequence from [Anas specularioides] with SO4 and ZN as [ligands]. Structure known Active Site: ZN. Full crystallographic information is available from [OCA].
Reference
Crystal structure of avian carboxypeptidase D domain II: a prototype for the regulatory metallocarboxypeptidase subfamily., Gomis-Ruth FX, Companys V, Qian Y, Fricker LD, Vendrell J, Aviles FX, Coll M, EMBO J. 1999 Nov 1;18(21):5817-26. PMID:10545093
Page seeded by OCA on Tue Oct 30 14:27:36 2007
