1k4h

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(New page: 200px<br /><applet load="1k4h" size="450" color="white" frame="true" align="right" spinBox="true" caption="1k4h, resolution 1.80&Aring;" /> '''CRYSTAL STRUCTURE OF...)
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[[Image:1k4h.jpg|left|200px]]<br /><applet load="1k4h" size="450" color="white" frame="true" align="right" spinBox="true"
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[[Image:1k4h.jpg|left|200px]]<br /><applet load="1k4h" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1k4h, resolution 1.80&Aring;" />
caption="1k4h, resolution 1.80&Aring;" />
'''CRYSTAL STRUCTURE OF TRNA-GUANINE TRANSGLYCOSYLASE (TGT) COMPLEXED WITH 2,6-Diamino-8-propylsulfanylmethyl-3H-quinazoline-4-one'''<br />
'''CRYSTAL STRUCTURE OF TRNA-GUANINE TRANSGLYCOSYLASE (TGT) COMPLEXED WITH 2,6-Diamino-8-propylsulfanylmethyl-3H-quinazoline-4-one'''<br />
==About this Structure==
==About this Structure==
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1K4H is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis] with ZN and APQ as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Queuine_tRNA-ribosyltransferase Queuine tRNA-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.29 2.4.2.29] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1K4H OCA].
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1K4H is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=APQ:'>APQ</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Queuine_tRNA-ribosyltransferase Queuine tRNA-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.29 2.4.2.29] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K4H OCA].
==Reference==
==Reference==
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[[Category: Zymomonas mobilis]]
[[Category: Zymomonas mobilis]]
[[Category: Brenk, R.]]
[[Category: Brenk, R.]]
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[[Category: Castellano, R.K.]]
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[[Category: Castellano, R K.]]
[[Category: Diederich, F.]]
[[Category: Diederich, F.]]
[[Category: Furler, M.]]
[[Category: Furler, M.]]
[[Category: Klebe, G.]]
[[Category: Klebe, G.]]
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[[Category: Meyer, E.A.]]
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[[Category: Meyer, E A.]]
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[[Category: Stubbs, M.T.]]
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[[Category: Stubbs, M T.]]
[[Category: APQ]]
[[Category: APQ]]
[[Category: ZN]]
[[Category: ZN]]
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[[Category: trna-modifying enzyme]]
[[Category: trna-modifying enzyme]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 18:51:08 2007''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:30:07 2008''

Revision as of 11:30, 21 February 2008


1k4h, resolution 1.80Å

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CRYSTAL STRUCTURE OF TRNA-GUANINE TRANSGLYCOSYLASE (TGT) COMPLEXED WITH 2,6-Diamino-8-propylsulfanylmethyl-3H-quinazoline-4-one

About this Structure

1K4H is a Single protein structure of sequence from Zymomonas mobilis with and as ligands. Active as Queuine tRNA-ribosyltransferase, with EC number 2.4.2.29 Full crystallographic information is available from OCA.

Reference

De novo design, synthesis, and in vitro evaluation of inhibitors for prokaryotic tRNA-guanine transglycosylase: a dramatic sulfur effect on binding affinity., Meyer EA, Brenk R, Castellano RK, Furler M, Klebe G, Diederich F, Chembiochem. 2002 Mar 1;3(2-3):250-3. PMID:11921407

Page seeded by OCA on Thu Feb 21 13:30:07 2008

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