2wd7

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[[Image:2wd7.png|left|200px]]
[[Image:2wd7.png|left|200px]]
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{{STRUCTURE_2wd7| PDB=2wd7 | SCENE= }}
{{STRUCTURE_2wd7| PDB=2wd7 | SCENE= }}
===PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH NADP AND DDD00066750===
===PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH NADP AND DDD00066750===
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{{ABSTRACT_PUBMED_19527033}}
{{ABSTRACT_PUBMED_19527033}}
==About this Structure==
==About this Structure==
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[[2wd7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WD7 OCA].
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[[2wd7]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WD7 OCA].
==Reference==
==Reference==
<ref group="xtra">PMID:019527033</ref><references group="xtra"/>
<ref group="xtra">PMID:019527033</ref><references group="xtra"/>
[[Category: Pteridine reductase]]
[[Category: Pteridine reductase]]
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[[Category: Trypanosoma brucei brucei]]
 
[[Category: Brenk, R.]]
[[Category: Brenk, R.]]
[[Category: Robinson, D A.]]
[[Category: Robinson, D A.]]

Revision as of 06:22, 10 October 2012

Template:STRUCTURE 2wd7

PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH NADP AND DDD00066750

Template:ABSTRACT PUBMED 19527033

About this Structure

2wd7 is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Mpamhanga CP, Spinks D, Tulloch LB, Shanks EJ, Robinson DA, Collie IT, Fairlamb AH, Wyatt PG, Frearson JA, Hunter WN, Gilbert IH, Brenk R. One Scaffold, Three Binding Modes: Novel and Selective Pteridine Reductase 1 Inhibitors Derived from Fragment Hits Discovered by Virtual Screening. J Med Chem. 2009 Jun 15. PMID:19527033 doi:10.1021/jm900414x

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