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2bff
From Proteopedia
(Difference between revisions)
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[[Image:2bff.png|left|200px]] | [[Image:2bff.png|left|200px]] | ||
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| - | The line below this paragraph, containing "STRUCTURE_2bff", creates the "Structure Box" on the page. | ||
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{{STRUCTURE_2bff| PDB=2bff | SCENE= }} | {{STRUCTURE_2bff| PDB=2bff | SCENE= }} | ||
| - | === | + | ===Reactivity modulation of human branched-chain alpha-ketoacid dehydrogenase by an internal molecular switch=== |
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| - | The line below this paragraph, {{ABSTRACT_PUBMED_16472748}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 16472748 is the PubMed ID number. | ||
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{{ABSTRACT_PUBMED_16472748}} | {{ABSTRACT_PUBMED_16472748}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2bff]] is a 2 chain structure | + | [[2bff]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BFF OCA]. |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:016472748</ref><ref group="xtra">PMID:015166214</ref><ref group="xtra">PMID:012902323</ref><references group="xtra"/> | + | <ref group="xtra">PMID:016472748</ref><ref group="xtra">PMID:015166214</ref><ref group="xtra">PMID:012902323</ref><ref group="xtra">PMID:011069910</ref><references group="xtra"/> |
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[[Category: Brautigam, C A.]] | [[Category: Brautigam, C A.]] | ||
[[Category: Chuang, D T.]] | [[Category: Chuang, D T.]] | ||
Revision as of 06:27, 10 October 2012
Reactivity modulation of human branched-chain alpha-ketoacid dehydrogenase by an internal molecular switch
Template:ABSTRACT PUBMED 16472748
About this Structure
2bff is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- Machius M, Wynn RM, Chuang JL, Li J, Kluger R, Yu D, Tomchick DR, Brautigam CA, Chuang DT. A versatile conformational switch regulates reactivity in human branched-chain alpha-ketoacid dehydrogenase. Structure. 2006 Feb;14(2):287-98. PMID:16472748 doi:10.1016/j.str.2005.10.009
- Li J, Wynn RM, Machius M, Chuang JL, Karthikeyan S, Tomchick DR, Chuang DT. Cross-talk between thiamin diphosphate binding and phosphorylation loop conformation in human branched-chain alpha-keto acid decarboxylase/dehydrogenase. J Biol Chem. 2004 Jul 30;279(31):32968-78. Epub 2004 May 27. PMID:15166214 doi:http://dx.doi.org/10.1074/jbc.M403611200
- Wynn RM, Machius M, Chuang JL, Li J, Tomchick DR, Chuang DT. Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase: refined phosphorylation loop structure in the active site. J Biol Chem. 2003 Oct 31;278(44):43402-10. Epub 2003 Aug 5. PMID:12902323 doi:http://dx.doi.org/10.1074/jbc.M306204200
- Wynn RM, Ho R, Chuang JL, Chuang DT. Roles of active site and novel K+ ion-binding site residues in human mitochondrial branched-chain alpha-ketoacid decarboxylase/dehydrogenase. J Biol Chem. 2001 Feb 9;276(6):4168-74. Epub 2000 Nov 7. PMID:11069910 doi:10.1074/jbc.M008038200
