3twj

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	{{STRUCTURE_3twj| PDB=3twj | SCENE= }}		{{STRUCTURE_3twj| PDB=3twj | SCENE= }}

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Revision as of 05:50, 17 October 2012

Template:STRUCTURE 3twj

Rho-associated protein kinase 1 (ROCK 1) IN COMPLEX WITH RKI1447

Template:ABSTRACT PUBMED 22846914

About this Structure

3twj is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Patel RA, Forinash KD, Pireddu R, Sun Y, Sun N, Martin MP, Schonbrunn E, Lawrence NJ, Sebti SM. RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and anti-tumor activities in breast cancer. Cancer Res. 2012 Jul 30. PMID:22846914 doi:10.1158/0008-5472.CAN-12-0954