1kvo
From Proteopedia
(New page: 200px<br /> <applet load="1kvo" size="450" color="white" frame="true" align="right" spinBox="true" caption="1kvo, resolution 2.0Å" /> '''HUMAN PHOSPHOLIPASE ...) |
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| - | [[Image:1kvo.gif|left|200px]]<br /> | + | [[Image:1kvo.gif|left|200px]]<br /><applet load="1kvo" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="1kvo" size=" | + | |
caption="1kvo, resolution 2.0Å" /> | caption="1kvo, resolution 2.0Å" /> | ||
'''HUMAN PHOSPHOLIPASE A2 COMPLEXED WITH A HIGHLY POTENT SUBSTRATE ANOLOGUE'''<br /> | '''HUMAN PHOSPHOLIPASE A2 COMPLEXED WITH A HIGHLY POTENT SUBSTRATE ANOLOGUE'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1KVO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with CA and OAP as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] Full crystallographic information is available from [http:// | + | 1KVO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=OAP:'>OAP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KVO OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Phospholipase A(2)]] | [[Category: Phospholipase A(2)]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Abdel-Meguid, S | + | [[Category: Abdel-Meguid, S S.]] |
| - | [[Category: Cha, S | + | [[Category: Cha, S S.]] |
| - | [[Category: Oh, B | + | [[Category: Oh, B H.]] |
[[Category: CA]] | [[Category: CA]] | ||
[[Category: OAP]] | [[Category: OAP]] | ||
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[[Category: signal]] | [[Category: signal]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:38:31 2008'' |
Revision as of 11:38, 21 February 2008
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HUMAN PHOSPHOLIPASE A2 COMPLEXED WITH A HIGHLY POTENT SUBSTRATE ANOLOGUE
Disease
Known diseases associated with this structure: Colorectal cancer, sporadic OMIM:[172411]
About this Structure
1KVO is a Single protein structure of sequence from Homo sapiens with and as ligands. Active as Phospholipase A(2), with EC number 3.1.1.4 Full crystallographic information is available from OCA.
Reference
High-resolution X-ray crystallography reveals precise binding interactions between human nonpancreatic secreted phospholipase A2 and a highly potent inhibitor (FPL67047XX)., Cha SS, Lee D, Adams J, Kurdyla JT, Jones CS, Marshall LA, Bolognese B, Abdel-Meguid SS, Oh BH, J Med Chem. 1996 Sep 27;39(20):3878-81. PMID:8831753
Page seeded by OCA on Thu Feb 21 13:38:31 2008
Categories: Homo sapiens | Phospholipase A(2) | Single protein | Abdel-Meguid, S S. | Cha, S S. | Oh, B H. | CA | OAP | Calcium | Hydrolase | Lipid degradation | Membrane | Signal
