Serpin

Serpin or serine protease inhibitor (Ser) are protease inhibitors. Ser E1 is antithrombin. Ser C1 is antithrombin . Ser A5 is protein C inhibitor. Ser A6 is a cortisol-binding globulin. Ser A8 is angiotensinogen. Ser A7 is a thyroxine-binding globulin. Ser B3 is squamos cell carcinoma antigen 1. Ser I1 is neuroserpin. Ser A10 is protein Z-related protease inhibitor. Ser A1 is alpha-1 antitrypsin. Ser E1 is plasminogen activator inhibitor 1.

‬

3D structures of serpin

Ser

1mtp, 1sng – Ser – Thermobifida fusca

Ser A1

3ndd, 3ndf, 3ne4 – hSer-A1 – human
3t1p – hSer-A1 (mutant)

Ser A5

2ol2 – hSer-A5
3dy0 – hSer-A5 + heparin

Ser A6

2v95 – rSer-A6 – rat
2vdx – hSer-A6 (mutant)
‪2vdx – hSer-A6 (mutant) + cortisol‬

Ser A7

2riv – hSer-A7
2riw – hSer-A7 + thyroxine
2xn3 – hSer-A7 + mefenamic acid
2xn5 – hSer-A7 + furosemide
2xn6, 2xn7 – hSer-A7 + thyroxine-fluoresein

Ser A8

2jp8 – hSer-A8 – NMR
2wxw – hSer-A8
2x0b – hSer-A8 + renin
2wxx, 2wxy, 2wy0 – Ser-A8 – mouse
2wxz, 2wy1 – rSer-A8

Ser A10

3h5c, 3f1s – hSer-A10 + vitamin K-dependent protein Z

Ser B3

2zv6 – hSer-B3

Ser C1

Antithrombin

Ser E1

Plasminogen activator inhibitor

Ser E2

4dy0 – hSer-E2 + heparin

Ser-I1

3fgq, 2f02, 3f5n – hSer-I1

Ser K

1sek – ThSer-K – Tobacco hornworm

Ser 1

1k9o – ThSer-1 (mutant) + trypsin II
3le2 – Ser-1 – Arabidopsis thaliana

Ser 2

1m93 – Ser-2 – Cowpox virus
3nda – Ser-2 – Sheep tick
3pzf – Ser-2 – malaria mosquito

Maspin

1xqg, 1xqj, 1wz9, 1xu8 - hMapsin