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1sa4

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==About this Structure==
==About this Structure==
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[[1sa4]] is a 2 chain structure of [[Farnesyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SA4 OCA].
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[[1sa4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SA4 OCA].
==See Also==
==See Also==

Revision as of 05:15, 20 October 2012

Image:1sa4.png

Template:STRUCTURE 1sa4

Contents

human protein farnesyltransferase complexed with FPP and R115777

Template:ABSTRACT PUBMED 15170324

About this Structure

1sa4 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Reid TS, Beese LS. Crystal structures of the anticancer clinical candidates R115777 (Tipifarnib) and BMS-214662 complexed with protein farnesyltransferase suggest a mechanism of FTI selectivity. Biochemistry. 2004 Jun 8;43(22):6877-84. PMID:15170324 doi:10.1021/bi049723b

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