1sa4
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[1sa4]] is a 2 chain structure | + | [[1sa4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SA4 OCA]. |
==See Also== | ==See Also== | ||
Revision as of 05:15, 20 October 2012
Contents |
human protein farnesyltransferase complexed with FPP and R115777
Template:ABSTRACT PUBMED 15170324
About this Structure
1sa4 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Reid TS, Beese LS. Crystal structures of the anticancer clinical candidates R115777 (Tipifarnib) and BMS-214662 complexed with protein farnesyltransferase suggest a mechanism of FTI selectivity. Biochemistry. 2004 Jun 8;43(22):6877-84. PMID:15170324 doi:10.1021/bi049723b
Categories: Homo sapiens | Protein farnesyltransferase | Beese, L S. | Reid, T S. | Caax | Cancer | Clinical candidate | Farnesyl transferase | Farnesyltransferase | Ftase | Fti | Inhibitor | Lipid modification | Protein prenylation | R115777 | Ra | Tipifarnib | Transferase | Tumor regression | Zarnestra
