3ik3
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[3ik3]] is a 2 chain structure | + | [[3ik3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IK3 OCA]. |
==See Also== | ==See Also== | ||
Revision as of 05:16, 20 October 2012
Contents |
AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance
Template:ABSTRACT PUBMED 19878872
About this Structure
3ik3 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
See Also
Reference
- O'Hare T, Shakespeare WC, Zhu X, Eide CA, Rivera VM, Wang F, Adrian LT, Zhou T, Huang WS, Xu Q, Metcalf CA 3rd, Tyner JW, Loriaux MM, Corbin AS, Wardwell S, Ning Y, Keats JA, Wang Y, Sundaramoorthi R, Thomas M, Zhou D, Snodgrass J, Commodore L, Sawyer TK, Dalgarno DC, Deininger MW, Druker BJ, Clackson T. AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance. Cancer Cell. 2009 Nov 6;16(5):401-12. PMID:19878872 doi:10.1016/j.ccr.2009.09.028
Categories: Mus musculus | Non-specific protein-tyrosine kinase | Zhou, T. | Atp-binding | Bcr-abl | Cell adhesion | Cml | Cytoskeleton | Drug resistance | Inhibitor | Kinase | Lipoprotein | Magnesium | Manganese | Metal-binding | Mutation | Myristate | Nucleotide-binding | Nucleus | Phosphoprotein | Proto-oncogene | Sh2 domain | Sh3 domain | T315i | Transferase
