3i25
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[3i25]] is a 3 chain structure | + | [[3i25]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I25 OCA]. |
==See Also== | ==See Also== | ||
Revision as of 07:44, 20 October 2012
Contents |
Potent Beta-Secretase 1 hydroxyethylene Inhibitor
Template:ABSTRACT PUBMED 20122837
About this Structure
3i25 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Bjorklund C, Adolfsson H, Jansson K, Lindberg J, Vrang L, Hallberg A, Rosenquist S, Samuelsson B. Discovery of potent BACE-1 inhibitors containing a new hydroxyethylene (HE) scaffold: exploration of P1' alkoxy residues and an aminoethylene (AE) central core. Bioorg Med Chem. 2010 Feb 15;18(4):1711-23. Epub 2010 Jan 11. PMID:20122837 doi:10.1016/j.bmc.2009.12.051
Categories: Homo sapiens | Memapsin 2 | Borkakoti, N. | Lindberg, J D. | Nystrom, S. | Aspartyl protease | Bace | Beta-secretase | Disulfide bond | Glycoprotein | Hydrolase | Inhibitor | Membrane | Protease | Transmembrane | Zymogen
