2oj9
From Proteopedia
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[[Image:2oj9.png|left|200px]] | [[Image:2oj9.png|left|200px]] | ||
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{{STRUCTURE_2oj9| PDB=2oj9 | SCENE= }} | {{STRUCTURE_2oj9| PDB=2oj9 | SCENE= }} | ||
===Structure of IGF-1R kinase domain complexed with a benzimidazole inhibitor=== | ===Structure of IGF-1R kinase domain complexed with a benzimidazole inhibitor=== | ||
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| - | (as it appears on PubMed at http://www.pubmed.gov), where 17317169 is the PubMed ID number. | ||
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{{ABSTRACT_PUBMED_17317169}} | {{ABSTRACT_PUBMED_17317169}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Insulin-like growth factor I, resistance to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147370 147370]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2oj9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OJ9 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Insulin-like growth factor receptor|Insulin-like growth factor receptor]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017317169</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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[[Category: Igf-1r]] | [[Category: Igf-1r]] | ||
[[Category: Kinase domain]] | [[Category: Kinase domain]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 07:54, 20 October 2012
Contents |
Structure of IGF-1R kinase domain complexed with a benzimidazole inhibitor
Template:ABSTRACT PUBMED 17317169
About this Structure
2oj9 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Velaparthi U, Wittman M, Liu P, Stoffan K, Zimmermann K, Sang X, Carboni J, Li A, Attar R, Gottardis M, Greer A, Chang CY, Jacobsen BL, Sack JS, Sun Y, Langley DR, Balasubramanian B, Vyas D. Discovery and initial SAR of 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-ones as inhibitors of insulin-like growth factor 1-receptor (IGF-1R). Bioorg Med Chem Lett. 2007 Apr 15;17(8):2317-21. Epub 2007 Feb 4. PMID:17317169 doi:10.1016/j.bmcl.2007.01.102
