4dl5
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[4dl5]] is a 3 chain structure | + | [[4dl5]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DL5 OCA]. |
==See Also== | ==See Also== | ||
Revision as of 08:21, 20 October 2012
Contents |
Human DNA polymerase eta inserting dCMPNPP opposite the 5'G of cisplatin crosslinked Gs (Pt-GG2).
Template:ABSTRACT PUBMED 22529383
About this Structure
4dl5 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Zhao Y, Biertumpfel C, Gregory MT, Hua YJ, Hanaoka F, Yang W. Structural basis of human DNA polymerase eta-mediated chemoresistance to cisplatin. Proc Natl Acad Sci U S A. 2012 Apr 23. PMID:22529383 doi:10.1073/pnas.1202681109
Categories: DNA-directed DNA polymerase | Homo sapiens | Biertumpfel, Christian | Gregory, M. | Hanaoka, F. | Hua, Y. | Yang, W. | Zhao, Y. | Chemoresistence | Cisplatin | Dna distorsion | Human dna polymerse eta | Inhibition | Kinetic | Molecular splint | Nucleotidyl transfer reaction | Pcna | Second tls polymerase | Transferase-dna-inhibitor complex | Translesion synthesis
