3b2r
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
- | [[3b2r]] is a 2 chain structure | + | [[3b2r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B2R OCA]. |
==See Also== | ==See Also== |
Revision as of 08:38, 20 October 2012
Contents |
Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil
Template:ABSTRACT PUBMED 17959709
About this Structure
3b2r is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wang H, Ye M, Robinson H, Francis SH, Ke H. Conformational variations of both phosphodiesterase-5 and inhibitors provide the structural basis for the physiological effects of vardenafil and sildenafil. Mol Pharmacol. 2008 Jan;73(1):104-10. Epub 2007 Oct 24. PMID:17959709 doi:10.1124/mol.107.040212
Categories: 3',5'-cyclic-GMP phosphodiesterase | Homo sapiens | Hengming, K. | Howard, R. | Huanchen, W. | Mengchun, Y. | Sharron, H F. | Allosteric enzyme | Cgmp phosphodiesterase | Cgmp-binding | Hydrolase | Levitratm. | Magnesium | Metal-binding | Nucleotide-binding | Pde5-inhibitor potency | Phosphorylation | Sildenafil | Vardenafil