1ln4
From Proteopedia
(New page: 200px<br /><applet load="1ln4" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ln4, resolution 1.5Å" /> '''CRYSTAL STRUCTURE OF ...) |
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| - | [[Image:1ln4.jpg|left|200px]]<br /><applet load="1ln4" size=" | + | [[Image:1ln4.jpg|left|200px]]<br /><applet load="1ln4" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1ln4, resolution 1.5Å" /> | caption="1ln4, resolution 1.5Å" /> | ||
'''CRYSTAL STRUCTURE OF E. COLI YHBY'''<br /> | '''CRYSTAL STRUCTURE OF E. COLI YHBY'''<br /> | ||
==Overview== | ==Overview== | ||
| - | E. coli YhbY belongs to a conserved family of hypothetical proteins | + | E. coli YhbY belongs to a conserved family of hypothetical proteins represented in eubacteria, archaea, and plants (Pfam code UPF0044). Three maize proteins harboring UPF0044-like domains are required for chloroplast group II intron splicing, and bioinformatic data suggest a role for prokaryotic UPF0044 members in translation. The crystal structure of YhbY has been determined. YhbY has a fold similar to that of the C-terminal domain of translation initiation factor 3 (IF3C), which binds to 16S rRNA in the 30S ribosome. Modeling studies indicate that the same surface is highly basic in all members of UPF0044, suggesting a conserved RNA binding surface. Taken together, the evidence suggests that members of UPF0044 constitute a previously unrecognized class of RNA binding domain. |
==About this Structure== | ==About this Structure== | ||
| - | 1LN4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http:// | + | 1LN4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LN4 OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Barkan, A.]] | [[Category: Barkan, A.]] | ||
| - | [[Category: Matthews, B | + | [[Category: Matthews, B W.]] |
| - | [[Category: Ostheimer, G | + | [[Category: Ostheimer, G J.]] |
[[Category: putative rna-binding protein; putative translation factor]] | [[Category: putative rna-binding protein; putative translation factor]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:46:28 2008'' |
Revision as of 11:46, 21 February 2008
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CRYSTAL STRUCTURE OF E. COLI YHBY
Overview
E. coli YhbY belongs to a conserved family of hypothetical proteins represented in eubacteria, archaea, and plants (Pfam code UPF0044). Three maize proteins harboring UPF0044-like domains are required for chloroplast group II intron splicing, and bioinformatic data suggest a role for prokaryotic UPF0044 members in translation. The crystal structure of YhbY has been determined. YhbY has a fold similar to that of the C-terminal domain of translation initiation factor 3 (IF3C), which binds to 16S rRNA in the 30S ribosome. Modeling studies indicate that the same surface is highly basic in all members of UPF0044, suggesting a conserved RNA binding surface. Taken together, the evidence suggests that members of UPF0044 constitute a previously unrecognized class of RNA binding domain.
About this Structure
1LN4 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Crystal structure of E. coli YhbY: a representative of a novel class of RNA binding proteins., Ostheimer GJ, Barkan A, Matthews BW, Structure. 2002 Nov;10(11):1593-601. PMID:12429100
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