3dds
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
- | [[3dds]] is a 2 chain structure | + | [[3dds]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DDS OCA]. |
==See Also== | ==See Also== |
Revision as of 09:48, 20 October 2012
Contents |
Crystal structure of glycogen phosphorylase complexed with an anthranilimide based inhibitor GSK261
Template:ABSTRACT PUBMED 19138846
About this Structure
3dds is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Thomson SA, Banker P, Bickett DM, Boucheron JA, Carter HL, Clancy DC, Cooper JP, Dickerson SH, Garrido DM, Nolte RT, Peat AJ, Sheckler LR, Sparks SM, Tavares FX, Wang L, Wang TY, Weiel JE. Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1177-82. Epub 2008 Dec 25. PMID:19138846 doi:10.1016/j.bmcl.2008.12.085
Categories: Homo sapiens | Phosphorylase | Nolte, R T. | Allosteric enzyme | Carbohydrate metabolism | Diabetes | Disease mutation | Glycogen metabolism | Glycogen phosphorylase | Glycogen storage disease | Glycosyltransferase | Gp | Nucleotide-binding | Phosphoprotein | Pyridoxal phosphate | Transferase