1lud
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1lud" size="450" color="white" frame="true" align="right" spinBox="true" caption="1lud" /> '''SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTAS...) |
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- | [[Image:1lud.gif|left|200px]]<br /><applet load="1lud" size=" | + | [[Image:1lud.gif|left|200px]]<br /><applet load="1lud" size="350" color="white" frame="true" align="right" spinBox="true" |
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'''SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES'''<br /> | '''SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES'''<br /> | ||
==About this Structure== | ==About this Structure== | ||
- | 1LUD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Lactobacillus_casei Lactobacillus casei] with NDP and TRR as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] Full crystallographic information is available from [http:// | + | 1LUD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Lactobacillus_casei Lactobacillus casei] with <scene name='pdbligand=NDP:'>NDP</scene> and <scene name='pdbligand=TRR:'>TRR</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LUD OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Feeney, J.]] | [[Category: Feeney, J.]] | ||
[[Category: Kelly, G.]] | [[Category: Kelly, G.]] | ||
- | [[Category: Polshakov, V | + | [[Category: Polshakov, V I.]] |
- | [[Category: Smirnov, E | + | [[Category: Smirnov, E G.]] |
[[Category: NDP]] | [[Category: NDP]] | ||
[[Category: TRR]] | [[Category: TRR]] | ||
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[[Category: inhibitor/enzyme complex]] | [[Category: inhibitor/enzyme complex]] | ||
- | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:48:31 2008'' |
Revision as of 11:48, 21 February 2008
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SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES
About this Structure
1LUD is a Single protein structure of sequence from Lactobacillus casei with and as ligands. Active as Dihydrofolate reductase, with EC number 1.5.1.3 Full crystallographic information is available from OCA.
Reference
NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH., Polshakov VI, Smirnov EG, Birdsall B, Kelly G, Feeney J, J Biomol NMR. 2002 Sep;24(1):67-70. PMID:12449420
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