3gnv
From Proteopedia
m (Protected "3gnv" [edit=sysop:move=sysop]) |
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==About this Structure== | ==About this Structure== | ||
| - | [[3gnv]] is a 2 chain structure | + | [[3gnv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_isolate_hc-j4 Hepatitis c virus isolate hc-j4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GNV OCA]. |
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:019507864</ref><references group="xtra"/> | <ref group="xtra">PMID:019507864</ref><references group="xtra"/> | ||
| - | [[Category: Hepatitis c virus isolate]] | + | [[Category: Hepatitis c virus isolate hc-j4]] |
[[Category: RNA-directed RNA polymerase]] | [[Category: RNA-directed RNA polymerase]] | ||
[[Category: Bondt, H De.]] | [[Category: Bondt, H De.]] | ||
Revision as of 10:26, 20 October 2012
Contents |
HCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 1b
Template:ABSTRACT PUBMED 19507864
About this Structure
3gnv is a 2 chain structure with sequence from Hepatitis c virus isolate hc-j4. Full crystallographic information is available from OCA.
See Also
Reference
- Vandyck K, Cummings MD, Nyanguile O, Boutton CW, Vendeville S, McGowan D, Devogelaere B, Amssoms K, Last S, Rombauts K, Tahri A, Lory P, Hu L, Beauchamp DA, Simmen K, Raboisson P. Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase. J Med Chem. 2009 Jul 23;52(14):4099-102. PMID:19507864 doi:10.1021/jm9005548
Categories: Hepatitis c virus isolate hc-j4 | RNA-directed RNA polymerase | Bondt, H De. | Nyanguile, O. | 1 5-benzodiazepine | Apoptosis | Atp-binding | Capsid protein | Cell membrane | Endoplasmic reticulum | Envelope protein | Fusion protein | Glycoprotein | Helicase | Hepatitis c virus | Host-virus interaction | Hydrolase | Interferon antiviral system evasion | Lipid droplet | Lipoprotein | Membrane | Metal-binding | Mitochondrion | Multifunctional enzyme | Ns5b | Nucleotide-binding | Nucleotidyltransferase | Nucleus | Oncogene | Palmitate | Phosphoprotein | Polymerase | Protease | Ribonucleoprotein | Rna replication | Rna-binding | Rna-directed rna polymerase | Secreted | Serine protease | Sh3-binding | Sulfone | Thiol protease | Transcription | Transcription regulation | Transferase | Transmembrane | Viral nucleoprotein | Virion
