2g20
From Proteopedia
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[[Image:2g20.png|left|200px]] | [[Image:2g20.png|left|200px]] | ||
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{{STRUCTURE_2g20| PDB=2g20 | SCENE= }} | {{STRUCTURE_2g20| PDB=2g20 | SCENE= }} | ||
===Ketopiperazine-Based Renin Inhibitors: Optimization of the C Ring=== | ===Ketopiperazine-Based Renin Inhibitors: Optimization of the C Ring=== | ||
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{{ABSTRACT_PUBMED_16480874}} | {{ABSTRACT_PUBMED_16480874}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Renal tubular dysgenesis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=179820 179820]], Hyperproreninemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=179820 179820]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2g20]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G20 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Renin|Renin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016480874</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Renin]] | [[Category: Renin]] | ||
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[[Category: Mcconnella, P.]] | [[Category: Mcconnella, P.]] | ||
[[Category: Zhanga, E.]] | [[Category: Zhanga, E.]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Protein-ligand complex]] | [[Category: Protein-ligand complex]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:32:04 2009'' | ||
Revision as of 11:16, 20 October 2012
Contents |
Ketopiperazine-Based Renin Inhibitors: Optimization of the C Ring
Template:ABSTRACT PUBMED 16480874
About this Structure
2g20 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Holsworth DD, Cai C, Cheng XM, Cody WL, Downing DM, Erasga N, Lee C, Powell NA, Edmunds JJ, Stier M, Jalaie M, Zhang E, McConnell P, Ryan MJ, Bryant J, Li T, Kasani A, Hall E, Subedi R, Rahim M, Maiti S. Ketopiperazine-based renin inhibitors: optimization of the "C" ring. Bioorg Med Chem Lett. 2006 May 1;16(9):2500-4. Epub 2006 Feb 15. PMID:16480874 doi:http://dx.doi.org/10.1016/j.bmcl.2006.01.084
