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3bxq

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==About this Structure==
==About this Structure==
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[[3bxq]] is a 4 chain structure of [[Molecular Playground/Insulin]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BXQ OCA].
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[[3bxq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BXQ OCA].
==See Also==
==See Also==

Revision as of 11:37, 20 October 2012

Image:3bxq.png

Template:STRUCTURE 3bxq

Contents

The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition

Template:ABSTRACT PUBMED 18332129

About this Structure

3bxq is a 4 chain structure. Full crystallographic information is available from OCA.

See Also

Reference

  • Hua QX, Nakagawa SH, Jia W, Huang K, Phillips NB, Hu SQ, Weiss MA. Design of an active ultrastable single-chain insulin analog: synthesis, structure, and therapeutic implications. J Biol Chem. 2008 May 23;283(21):14703-16. Epub 2008 Mar 10. PMID:18332129 doi:10.1074/jbc.M800313200
  • Wan ZL, Huang K, Hu SQ, Whittaker J, Weiss MA. The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition. J Biol Chem. 2008 Jul 25;283(30):21198-210. Epub 2008 May 20. PMID:18492668 doi:10.1074/jbc.M800235200

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