3i6z
From Proteopedia
(Difference between revisions)
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3i6z]] is a 1 chain structure | + | [[3i6z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I6Z OCA]. |
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:020025280</ref><ref group="xtra">PMID:015563167</ref><ref group="xtra">PMID:010606746 | + | <ref group="xtra">PMID:020025280</ref><ref group="xtra">PMID:015563167</ref><ref group="xtra">PMID:010606746</ref><ref group="xtra">PMID:012140604</ref><ref group="xtra">PMID:016711737</ref><references group="xtra"/> |
[[Category: Acetylcholinesterase]] | [[Category: Acetylcholinesterase]] | ||
[[Category: Torpedo californica]] | [[Category: Torpedo californica]] | ||
Revision as of 11:42, 20 October 2012
Contents |
3D Structure of Torpedo californica acetylcholinesterase complexed with N-saccharinohexyl-galanthamine
Template:ABSTRACT PUBMED 20025280
About this Structure
3i6z is a 1 chain structure with sequence from Torpedo californica. Full crystallographic information is available from OCA.
See Also
Reference
- Bartolucci C, Haller LA, Jordis U, Fels G, Lamba D. Probing Torpedo californica Acetylcholinesterase Catalytic Gorge with Two Novel Bis-functional Galanthamine Derivatives. J Med Chem. 2009 Dec 21. PMID:20025280 doi:10.1021/jm901296p
- Greenblatt HM, Guillou C, Guenard D, Argaman A, Botti S, Badet B, Thal C, Silman I, Sussman JL. The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design. J Am Chem Soc. 2004 Dec 1;126(47):15405-11. PMID:15563167 doi:http://dx.doi.org/10.1021/ja0466154
- Greenblatt HM, Kryger G, Lewis T, Silman I, Sussman JL. Structure of acetylcholinesterase complexed with (-)-galanthamine at 2.3 A resolution. FEBS Lett. 1999 Dec 17;463(3):321-6. PMID:10606746
- Luttmann E, Linnemann E, Fels G. Galanthamine as bis-functional ligand for the acetylcholinesterase. J Mol Model. 2002 Jun;8(6):208-16. PMID:12140604 doi:10.1007/s00894-002-0086-9
- Alisaraie L, Haller LA, Fels G. A QXP-based multistep docking procedure for accurate prediction of protein-ligand complexes. J Chem Inf Model. 2006 May-Jun;46(3):1174-87. PMID:16711737 doi:10.1021/ci050343m
Categories: Acetylcholinesterase | Torpedo californica | Bartolucci, C. | Lamba, D. | Alzheimer's disease | Bis-functional galanthamine derivative | Cell junction | Cell membrane | Cholinesterase | Disulfide bond | Glycoprotein | Gpi-anchor | Hydrolase | Lipoprotein | Membrane | Neurotransmitter degradation | Serine esterase | Serine hydrolase | Synapse
