3ds6
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[3ds6]] is a 4 chain structure | + | [[3ds6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DS6 OCA]. |
==See Also== | ==See Also== | ||
Revision as of 13:00, 20 October 2012
Contents |
P38 complex with a phthalazine inhibitor
Template:ABSTRACT PUBMED 18817365
About this Structure
3ds6 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Herberich B, Cao GQ, Chakrabarti PP, Falsey JR, Pettus L, Rzasa RM, Reed AB, Reichelt A, Sham K, Thaman M, Wurz RP, Xu S, Zhang D, Hsieh F, Lee MR, Syed R, Li V, Grosfeld D, Plant MH, Henkle B, Sherman L, Middleton S, Wong LM, Tasker AS. Discovery of Highly Selective and Potent p38 Inhibitors Based on a Phthalazine Scaffold. J Med Chem. 2008 Sep 26. PMID:18817365 doi:10.1021/jm8005417
- Pettus LH, Xu S, Cao GQ, Chakrabarti PP, Rzasa RM, Sham K, Wurz RP, Zhang D, Middleton S, Henkle B, Plant MH, Saris CJ, Sherman L, Wong LM, Powers DA, Tudor Y, Yu V, Lee MR, Syed R, Hsieh F, Tasker AS. 3-amino-7-phthalazinylbenzoisoxazoles as a novel class of potent, selective, and orally available inhibitors of p38alpha mitogen-activated protein kinase. J Med Chem. 2008 Oct 23;51(20):6280-92. Epub 2008 Sep 26. PMID:18817364 doi:10.1021/jm8005405
