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3mf5

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==About this Structure==
==About this Structure==
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[[3mf5]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MF5 OCA].
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[[3mf5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MF5 OCA].
==See Also==
==See Also==

Revision as of 13:10, 20 October 2012

Image:3mf5.png

Template:STRUCTURE 3mf5

Contents

Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor

Template:ABSTRACT PUBMED 20584604

About this Structure

3mf5 is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

See Also

Reference

  • Yang H, Hendricks RT, Arora N, Nitzan D, Yee C, Lucas MC, Yang Y, Fung A, Rajyaguru S, Harris SF, Leveque VJ, Hang JQ, Pogam SL, Reuter D, Tavares GA. Cyclic amide bioisosterism: strategic application to the design and synthesis of HCV NS5B polymerase inhibitors. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4614-9. Epub 2010 Jun 8. PMID:20584604 doi:10.1016/j.bmcl.2010.06.008

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