3e8n
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[3e8n]] is a 1 chain structure | + | [[3e8n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E8N OCA]. |
==See Also== | ==See Also== | ||
Revision as of 14:37, 20 October 2012
Contents |
X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) complexed with a potent inhibitor RDEA119 and MgATP
Template:ABSTRACT PUBMED 19706763
About this Structure
3e8n is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Iverson C, Larson G, Lai C, Yeh LT, Dadson C, Weingarten P, Appleby T, Vo T, Maderna A, Vernier JM, Hamatake R, Miner JN, Quart B. RDEA119/BAY 869766: a potent, selective, allosteric inhibitor of MEK1/2 for the treatment of cancer. Cancer Res. 2009 Sep 1;69(17):6839-47. Epub 2009 Aug 25. PMID:19706763 doi:10.1158/0008-5472.CAN-09-0679
Categories: Homo sapiens | Mitogen-activated protein kinase kinase | Wang, Z M. | Yan, S. | Atp-binding | Disease mutation | Kinase | Mek1 | Mek1-rdea119 complex | Nucleotide-binding | Phosphoprotein | Protein kinase-ligand-mgatp complex | Rdea-119 | Rdea119 | Serine/threonine-protein kinase | Transferase | Tyrosine-protein kinase
