1mvp
From Proteopedia
(New page: 200px<br /><applet load="1mvp" size="450" color="white" frame="true" align="right" spinBox="true" caption="1mvp, resolution 2.2Å" /> '''STRUCTURAL STUDIES OF...) |
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| - | [[Image:1mvp.gif|left|200px]]<br /><applet load="1mvp" size=" | + | [[Image:1mvp.gif|left|200px]]<br /><applet load="1mvp" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1mvp, resolution 2.2Å" /> | caption="1mvp, resolution 2.2Å" /> | ||
'''STRUCTURAL STUDIES OF THE RETROVIRAL PROTEINASE FROM AVIAN MYELOBLASTOSIS ASSOCIATED VIRUS'''<br /> | '''STRUCTURAL STUDIES OF THE RETROVIRAL PROTEINASE FROM AVIAN MYELOBLASTOSIS ASSOCIATED VIRUS'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The structure of the retroviral proteinase from avian myeloblastosis | + | The structure of the retroviral proteinase from avian myeloblastosis associated virus (MAV) has been determined and refined at 2.2 A resolution. This structure is compared with those of homologous proteinases from Rous sarcoma virus (RSV) and human immunodeficiency type 1 virus (HIV). Through comparison with the structure of a proteinase-inhibitor complex from HIV, a model of a complex between MAV proteinase and a peptide substrate has been generated. Examination of this model suggests structural basis for the diverse specifications of viral proteinases. |
==About this Structure== | ==About this Structure== | ||
| - | 1MVP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Avian_myeloblastosis_associated_virus Avian myeloblastosis associated virus]. Full crystallographic information is available from [http:// | + | 1MVP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Avian_myeloblastosis_associated_virus Avian myeloblastosis associated virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MVP OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Avian myeloblastosis associated virus]] | [[Category: Avian myeloblastosis associated virus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Foundling, S | + | [[Category: Foundling, S I.]] |
| - | [[Category: Ohlendorf, D | + | [[Category: Ohlendorf, D H.]] |
| - | [[Category: Salemme, F | + | [[Category: Salemme, F R.]] |
[[Category: hydrolase(aspartic proteinase)]] | [[Category: hydrolase(aspartic proteinase)]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:59:31 2008'' |
Revision as of 11:59, 21 February 2008
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STRUCTURAL STUDIES OF THE RETROVIRAL PROTEINASE FROM AVIAN MYELOBLASTOSIS ASSOCIATED VIRUS
Overview
The structure of the retroviral proteinase from avian myeloblastosis associated virus (MAV) has been determined and refined at 2.2 A resolution. This structure is compared with those of homologous proteinases from Rous sarcoma virus (RSV) and human immunodeficiency type 1 virus (HIV). Through comparison with the structure of a proteinase-inhibitor complex from HIV, a model of a complex between MAV proteinase and a peptide substrate has been generated. Examination of this model suggests structural basis for the diverse specifications of viral proteinases.
About this Structure
1MVP is a Single protein structure of sequence from Avian myeloblastosis associated virus. Full crystallographic information is available from OCA.
Reference
Structural studies of the retroviral proteinase from avian myeloblastosis associated virus., Ohlendorf DH, Foundling SI, Wendoloski JJ, Sedlacek J, Strop P, Salemme FR, Proteins. 1992 Nov;14(3):382-91. PMID:1332025
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