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3fcu
From Proteopedia
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{{STRUCTURE_3fcu| PDB=3fcu | SCENE= }} | {{STRUCTURE_3fcu| PDB=3fcu | SCENE= }} | ||
===Structure of headpiece of integrin aIIBb3 in open conformation=== | ===Structure of headpiece of integrin aIIBb3 in open conformation=== | ||
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{{ABSTRACT_PUBMED_19111664}} | {{ABSTRACT_PUBMED_19111664}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Glanzmann thrombasthenia, type A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607759 607759]], Thrombocytopenia, neonatal alloimmune OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607759 607759]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3fcu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FCU OCA]. | |
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| + | ==See Also== | ||
| + | *[[Integrin|Integrin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019111664</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Luo, B H.]] | [[Category: Luo, B H.]] | ||
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[[Category: Zhu, J.]] | [[Category: Zhu, J.]] | ||
[[Category: Allostery]] | [[Category: Allostery]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Cell adhesion]] | [[Category: Cell adhesion]] | ||
| - | [[Category: Cell adhesion | + | [[Category: Cell adhesion-blood clotting complex]] |
| - | [[Category: Cell adhesion | + | [[Category: Cell adhesion-immune system complex]] |
[[Category: Crystal structure]] | [[Category: Crystal structure]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
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[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Platelet integrin alphaiibbeta3]] | [[Category: Platelet integrin alphaiibbeta3]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
[[Category: Therapeutic antagonism]] | [[Category: Therapeutic antagonism]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 21 10:49:26 2009'' | ||
Revision as of 15:27, 20 October 2012
Contents |
Structure of headpiece of integrin aIIBb3 in open conformation
Template:ABSTRACT PUBMED 19111664
About this Structure
3fcu is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Zhu J, Luo BH, Xiao T, Zhang C, Nishida N, Springer TA. Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Mol Cell. 2008 Dec 26;32(6):849-61. PMID:19111664 doi:10.1016/j.molcel.2008.11.018
Categories: Homo sapiens | Luo, B H. | Nishida, N. | Springer, T A. | Xiao, T. | Zhang, C. | Zhu, J. | Allostery | Cell adhesion | Cell adhesion-blood clotting complex | Cell adhesion-immune system complex | Crystal structure | Disease mutation | Fibrinogen binding | Glycoprotein | Host-virus interaction | Integrin | Membrane | Phosphoprotein | Platelet integrin alphaiibbeta3 | Receptor | Therapeutic antagonism | Transmembrane
