1a0k
From Proteopedia
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[[Category: profilin]] | [[Category: profilin]] | ||
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Revision as of 12:39, 30 October 2007
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PROFILIN I FROM ARABIDOPSIS THALIANA
Overview
BACKGROUND: Profilins are small eukaryotic proteins involved in modulating, the assembly of actin microfilaments in the cytoplasm. They are able to, bind both phosphatidylinositol-4,5-bisphosphate and poly-L-proline (PLP), and thus play a critical role in signaling pathways. Plant profilins are, of interest because immunological cross-reactivity between pollen and, human profilin may be the cause of hay fever and broad allergies to, pollens. RESULTS: The determination of the Arabidopsis thaliana profilin, isoform I structure, using multiwavelength anomalous diffraction (MAD) to, obtain structure-factor phases, is reported here. The structure of, Arabidopsis profilin is similar to that of previously determined profilin, structures. Conserved amino acid residues in profilins from plants, ... [(full description)]
About this Structure
1A0K is a [Single protein] structure of sequence from [Arabidopsis thaliana]. Structure known Active Sites: AIN, GOL and PLY. Full crystallographic information is available from [OCA].
Reference
The crystal structure of a major allergen from plants., Thorn KS, Christensen HE, Shigeta R, Huddler D, Shalaby L, Lindberg U, Chua NH, Schutt CE, Structure. 1997 Jan 15;5(1):19-32. PMID:9016723
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