3gw5
From Proteopedia
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{{STRUCTURE_3gw5| PDB=3gw5 | SCENE= }} | {{STRUCTURE_3gw5| PDB=3gw5 | SCENE= }} | ||
===Crystal structure of human renin complexed with a novel inhibitor=== | ===Crystal structure of human renin complexed with a novel inhibitor=== | ||
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| - | The line below this paragraph, {{ABSTRACT_PUBMED_19457666}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 19457666 is the PubMed ID number. | ||
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{{ABSTRACT_PUBMED_19457666}} | {{ABSTRACT_PUBMED_19457666}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Renal tubular dysgenesis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=179820 179820]], Hyperproreninemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=179820 179820]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3gw5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GW5 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Renin|Renin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019457666</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Renin]] | [[Category: Renin]] | ||
[[Category: McKeever, B M.]] | [[Category: McKeever, B M.]] | ||
[[Category: Wu, Z.]] | [[Category: Wu, Z.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Aspartate protease]] | [[Category: Aspartate protease]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
| - | [[Category: Crystal structure]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Disulfide bond]] | [[Category: Disulfide bond]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| - | [[Category: Hydrolase | + | [[Category: Hydrolase-hydrolase inhibitor complex]] |
[[Category: Hypertension]] | [[Category: Hypertension]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Renin]] | [[Category: Renin]] | ||
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[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 25 09:04:36 2009'' | ||
Revision as of 16:19, 20 October 2012
Contents |
Crystal structure of human renin complexed with a novel inhibitor
Template:ABSTRACT PUBMED 19457666
About this Structure
3gw5 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Tice CM, Xu Z, Yuan J, Simpson RD, Cacatian ST, Flaherty PT, Zhao W, Guo J, Ishchenko A, Singh SB, Wu Z, Scott BB, Bukhtiyarov Y, Berbaum J, Mason J, Panemangalore R, Cappiello MG, Muller D, Harrison RK, McGeehan GM, Dillard LW, Baldwin JJ, Claremon DA. Design and optimization of renin inhibitors: Orally bioavailable alkyl amines. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3541-5. Epub 2009 May 5. PMID:19457666 doi:10.1016/j.bmcl.2009.04.140
Categories: Homo sapiens | Renin | McKeever, B M. | Wu, Z. | Aspartate protease | Aspartyl protease | Cleavage on pair of basic residue | Disease mutation | Disulfide bond | Glycoprotein | Hydrolase | Hydrolase-hydrolase inhibitor complex | Hypertension | Membrane | Protease | Renin expression | Renin inhibitor | Secreted | Zymogen
