3cwj

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==About this Structure==
==About this Structure==
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[[3cwj]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CWJ OCA].
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[[3cwj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CWJ OCA].
==See Also==
==See Also==

Revision as of 16:30, 20 October 2012

Template:STRUCTURE 3cwj

Contents

Crystal structure of hcv ns5b polymerase with a novel pyridazinone inhibitor

Template:ABSTRACT PUBMED 18662878

About this Structure

3cwj is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

See Also

Reference

  • Ellis DA, Blazel JK, Webber SE, Tran CV, Dragovich PS, Sun Z, Ruebsam F, McGuire HM, Xiang AX, Zhao J, Li LS, Zhou Y, Han Q, Kissinger CR, Showalter RE, Lardy M, Shah AM, Tsan M, Patel R, LeBrun LA, Kamran R, Bartkowski DM, Nolan TG, Norris DA, Sergeeva MV, Kirkovsky L. 4-(1,1-Dioxo-1,4-dihydro-1lambda6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2H-pyr idazin-3-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4628-32. Epub 2008 Jul 10. PMID:18662878 doi:10.1016/j.bmcl.2008.07.014

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