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Template:STRUCTURE 2iko

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{{Structure
{{Structure
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[2iko]], resolution 1.90&Aring; (<scene name='initialview01'>default scene</scene>)}}}
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[2iko]], [[Resolution|resolution]] 1.90&Aring; (<scene name='initialview01'>default scene</scene>)}}}
|LIGAND= <scene name='pdbligand=7IG:5-{4-[(3,5-DIFLUOROBENZYL)AMINO]PHENYL}-6-ETHYLPYRIMIDINE-2,4-DIAMINE'>7IG</scene>
|LIGAND= <scene name='pdbligand=7IG:5-{4-[(3,5-DIFLUOROBENZYL)AMINO]PHENYL}-6-ETHYLPYRIMIDINE-2,4-DIAMINE'>7IG</scene>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Renin Renin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.15 3.4.23.15] </span>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Renin Renin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.15 3.4.23.15] </span>
|GENE= REN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= REN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00026 Asp]</span>
 
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iko OCA], [http://www.ebi.ac.uk/pdbsum/2iko PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2iko RCSB]</span>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iko OCA], [http://www.ebi.ac.uk/pdbsum/2iko PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2iko RCSB]</span>
|FUNCTION={{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0004194 | text = pepsin A activity}}{{GO|id=GO:0004195 | text = renin activity}}{{GO|id=GO:0005102 | text = receptor binding}}{{GO|id=GO:0004190 | text = aspartic-type endopeptidase activity}}
|FUNCTION={{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0004194 | text = pepsin A activity}}{{GO|id=GO:0004195 | text = renin activity}}{{GO|id=GO:0005102 | text = receptor binding}}{{GO|id=GO:0004190 | text = aspartic-type endopeptidase activity}}
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|COMPONENT={{GO|id=GO:0005615 | text = extracellular space}}{{GO|id=GO:0016020 | text = membrane}}
|COMPONENT={{GO|id=GO:0005615 | text = extracellular space}}{{GO|id=GO:0016020 | text = membrane}}
|SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR009007 Ipr009007], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001461 Ipr001461], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR012848 Ipr012848], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001969 Ipr001969]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00026 PF00026]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P00797 P00797]</span>
|SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR009007 Ipr009007], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001461 Ipr001461], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR012848 Ipr012848], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001969 Ipr001969]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00026 PF00026]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P00797 P00797]</span>
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|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=REN REN]</span>
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|uPDB=2IKO|CONSURF={{!}}-
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|CONSURF={{!}}-
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{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"

Revision as of 16:32, 20 October 2012

Drag the structure with the mouse to rotate
2iko, resolution 1.90Å ()
Ligands:
Gene: REN (Homo sapiens)
Activity: Renin, with EC number 3.4.23.15
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml


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