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2iko
From Proteopedia
(Difference between revisions)
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[[Image:2iko.png|left|200px]] | [[Image:2iko.png|left|200px]] | ||
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{{STRUCTURE_2iko| PDB=2iko | SCENE= }} | {{STRUCTURE_2iko| PDB=2iko | SCENE= }} | ||
===Crystal Structure of Human Renin Complexed with Inhibitor=== | ===Crystal Structure of Human Renin Complexed with Inhibitor=== | ||
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{{ABSTRACT_PUBMED_17113558}} | {{ABSTRACT_PUBMED_17113558}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Renal tubular dysgenesis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=179820 179820]], Hyperproreninemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=179820 179820]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2iko]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IKO OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Renin|Renin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017113558</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Renin]] | [[Category: Renin]] | ||
[[Category: Mochalkin, I.]] | [[Category: Mochalkin, I.]] | ||
[[Category: Drug design]] | [[Category: Drug design]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Renin]] | [[Category: Renin]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:54:58 2009'' | ||
Revision as of 16:32, 20 October 2012
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| 2iko, resolution 1.90Å () | |||||||||
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| Ligands: | |||||||||
| Gene: | REN (Homo sapiens) | ||||||||
| Activity: | Renin, with EC number 3.4.23.15 | ||||||||
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| |||||||||
| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
Crystal Structure of Human Renin Complexed with Inhibitor
Template:ABSTRACT PUBMED 17113558
About this Structure
2iko is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Sarver RW, Peevers J, Cody WL, Ciske FL, Dyer J, Emerson SD, Hagadorn JC, Holsworth DD, Jalaie M, Kaufman M, Mastronardi M, McConnell P, Powell NA, Quin J 3rd, Van Huis CA, Zhang E, Mochalkin I. Binding thermodynamics of substituted diaminopyrimidine renin inhibitors. Anal Biochem. 2007 Jan 1;360(1):30-40. Epub 2006 Oct 30. PMID:17113558 doi:http://dx.doi.org/10.1016/j.ab.2006.10.017
