2iko

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{{Seed}}
 
[[Image:2iko.png|left|200px]]
[[Image:2iko.png|left|200px]]
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{{STRUCTURE_2iko| PDB=2iko | SCENE= }}
{{STRUCTURE_2iko| PDB=2iko | SCENE= }}
===Crystal Structure of Human Renin Complexed with Inhibitor===
===Crystal Structure of Human Renin Complexed with Inhibitor===
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{{ABSTRACT_PUBMED_17113558}}
{{ABSTRACT_PUBMED_17113558}}
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==Disease==
 
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Known disease associated with this structure: Renal tubular dysgenesis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=179820 179820]], Hyperproreninemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=179820 179820]]
 
==About this Structure==
==About this Structure==
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2IKO is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IKO OCA].
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[[2iko]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IKO OCA].
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==See Also==
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*[[Renin|Renin]]
==Reference==
==Reference==
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<ref group="xtra">PMID:17113558</ref><references group="xtra"/>
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<ref group="xtra">PMID:017113558</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Renin]]
[[Category: Renin]]
[[Category: Mochalkin, I.]]
[[Category: Mochalkin, I.]]
[[Category: Drug design]]
[[Category: Drug design]]
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[[Category: Hydrolase]]
[[Category: Inhibitor]]
[[Category: Inhibitor]]
[[Category: Renin]]
[[Category: Renin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:54:58 2009''
 

Revision as of 16:32, 20 October 2012

Image:2iko.png


PDB ID 2iko

Drag the structure with the mouse to rotate
2iko, resolution 1.90Å ()
Ligands:
Gene: REN (Homo sapiens)
Activity: Renin, with EC number 3.4.23.15
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Contents

Crystal Structure of Human Renin Complexed with Inhibitor

Template:ABSTRACT PUBMED 17113558

About this Structure

2iko is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Sarver RW, Peevers J, Cody WL, Ciske FL, Dyer J, Emerson SD, Hagadorn JC, Holsworth DD, Jalaie M, Kaufman M, Mastronardi M, McConnell P, Powell NA, Quin J 3rd, Van Huis CA, Zhang E, Mochalkin I. Binding thermodynamics of substituted diaminopyrimidine renin inhibitors. Anal Biochem. 2007 Jan 1;360(1):30-40. Epub 2006 Oct 30. PMID:17113558 doi:http://dx.doi.org/10.1016/j.ab.2006.10.017

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OCA

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