1z3n
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[1z3n]] is a 1 chain structure | + | [[1z3n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z3N OCA]. |
==See Also== | ==See Also== | ||
Revision as of 16:36, 20 October 2012
Contents |
Human aldose reductase in complex with NADP+ and the inhibitor lidorestat at 1.04 angstrom
Template:ABSTRACT PUBMED 15857120
About this Structure
1z3n is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Van Zandt MC, Jones ML, Gunn DE, Geraci LS, Jones JH, Sawicki DR, Sredy J, Jacot JL, Dicioccio AT, Petrova T, Mitschler A, Podjarny AD. Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications. J Med Chem. 2005 May 5;48(9):3141-52. PMID:15857120 doi:10.1021/jm0492094
