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1n56
From Proteopedia
(New page: 200px<br /><applet load="1n56" size="450" color="white" frame="true" align="right" spinBox="true" caption="1n56, resolution 2.4Å" /> '''Y-family DNA polymera...) |
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| - | [[Image:1n56.gif|left|200px]]<br /><applet load="1n56" size=" | + | [[Image:1n56.gif|left|200px]]<br /><applet load="1n56" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1n56, resolution 2.4Å" /> | caption="1n56, resolution 2.4Å" /> | ||
'''Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion'''<br /> | '''Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion'''<br /> | ||
==Overview== | ==Overview== | ||
| - | Studies on several recently discovered error-prone DNA polymerases reveal | + | Studies on several recently discovered error-prone DNA polymerases reveal novel structures that may explain the low fidelity of this general class of enzymes, a number of which are involved in the replicative bypass (translesion synthesis) of base damage in DNA. |
==About this Structure== | ==About this Structure== | ||
| - | 1N56 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus] with MG, CA and ATP as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http:// | + | 1N56 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=ATP:'>ATP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N56 OCA]. |
==Reference== | ==Reference== | ||
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[[Category: y-family]] | [[Category: y-family]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:02:24 2008'' |
Revision as of 12:02, 21 February 2008
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Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion
Overview
Studies on several recently discovered error-prone DNA polymerases reveal novel structures that may explain the low fidelity of this general class of enzymes, a number of which are involved in the replicative bypass (translesion synthesis) of base damage in DNA.
About this Structure
1N56 is a Single protein structure of sequence from Sulfolobus solfataricus with , and as ligands. Full crystallographic information is available from OCA.
Reference
Error-prone DNA polymerases: novel structures and the benefits of infidelity., Friedberg EC, Fischhaber PL, Kisker C, Cell. 2001 Oct 5;107(1):9-12. PMID:11595180
Page seeded by OCA on Thu Feb 21 14:02:24 2008
Categories: Single protein | Sulfolobus solfataricus | Boudsocq, F. | Ling, H. | Woodgate, R. | Yang, W. | ATP | CA | MG | Dna lesion bypass | Dna polymerase | Protein-dna complex | Y-family
