3lj3
From Proteopedia
(Difference between revisions)
Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
- | [[3lj3]] is a 1 chain structure | + | [[3lj3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJ3 OCA]. |
==See Also== | ==See Also== |
Revision as of 16:40, 20 October 2012
Contents |
PI3-kinase-gamma with a pyrrolopyridine-benzofuran inhibitor
Template:ABSTRACT PUBMED 20188552
About this Structure
3lj3 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Tsou HR, MacEwan G, Birnberg G, Grosu G, Bursavich MG, Bard J, Brooijmans N, Toral-Barza L, Hollander I, Mansour TS, Ayral-Kaloustian S, Yu K. Discovery and optimization of 2-(4-substituted-pyrrolo[2,3-b]pyridin-3-yl)methylene-4-hydroxybenzofuran- 3(2H)-ones as potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR). Bioorg Med Chem Lett. 2010 Apr 1;20(7):2321-5. Epub 2010 Feb 2. PMID:20188552 doi:10.1016/j.bmcl.2010.01.135