3m36
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[3m36]] is a 2 chain structure | + | [[3m36]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M36 OCA]. |
==See Also== | ==See Also== | ||
Revision as of 16:52, 20 October 2012
Contents |
Factor XA in complex with the inhibitor 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423)
Template:ABSTRACT PUBMED 14640539
About this Structure
3m36 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Pruitt JR, Pinto DJ, Galemmo RA Jr, Alexander RS, Rossi KA, Wells BL, Drummond S, Bostrom LL, Burdick D, Bruckner R, Chen H, Smallwood A, Wong PC, Wright MR, Bai S, Luettgen JM, Knabb RM, Lam PY, Wexler RR. Discovery of 1-(2-aminomethylphenyl)-3-trifluoromethyl-N- [3-fluoro-2'-(aminosulfonyl)[1,1'-biphenyl)]-4-yl]-1H-pyrazole-5-carboxyam ide (DPC602), a potent, selective, and orally bioavailable factor Xa inhibitor(1). J Med Chem. 2003 Dec 4;46(25):5298-315. PMID:14640539 doi:10.1021/jm030212h
Categories: Coagulation factor Xa | Homo sapiens | Alexander, R S. | Blood coagulation | Blood coagulation factor | Calcium- binding | Cleavage on pair of basic residue | Disulfide bond | Egf-like domain | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Plasma | Protease | Protein inhibitor complex | Secreted | Serine protease | Zymogen
