3sx4
From Proteopedia
(Difference between revisions)
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3sx4]] is a 2 chain structure | + | [[3sx4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SX4 OCA]. |
==See Also== | ==See Also== | ||
Revision as of 17:10, 20 October 2012
Contents |
Crystal structure of human dpp-iv in complex with sa-(+)-3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyphenyl)- 2-methyl-5h-pyrrolo[3,4-b]pyridin-7(6h)-one
Template:ABSTRACT PUBMED 21996520
About this Structure
3sx4 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wang W, Devasthale P, Wang A, Harrity T, Egan D, Morgan N, Cap M, Fura A, Klei HE, Kish K, Weigelt C, Sun L, Levesque P, Li YX, Zahler R, Kirby MS, Hamann LG. 7-Oxopyrrolopyridine-derived DPP4 inhibitors-mitigation of CYP and hERG liabilities via introduction of polar functionalities in the active site. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6646-51. Epub 2011 Sep 24. PMID:21996520 doi:10.1016/j.bmcl.2011.09.074
Categories: Dipeptidyl-peptidase IV | Homo sapiens | Klei, H E. | Alpha/beta hydrolase fold | Aminopeptidase | Beta barrel | Beta propeller | Dimer | Dpp4 | Exopeptidase | Glycoprotein | Hydrolase-hydrolase inhibitor complex | Membrane | Protease | Protein:inhibitor complex | Secreted | Serine protease | Signal- anchor | Transmembrane
