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2bag

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==About this Structure==
==About this Structure==
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[[2bag]] is a 1 chain structure of [[Acetylcholinesterase]] with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BAG OCA].
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[[2bag]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BAG OCA].
==See Also==
==See Also==
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==Reference==
==Reference==
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<ref group="xtra">PMID:016913695</ref><ref group="xtra">PMID:010231521</ref><ref group="xtra">PMID:011888271</ref><ref group="xtra">PMID:009428657</ref><references group="xtra"/>
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<ref group="xtra">PMID:016913695</ref><ref group="xtra">PMID:010231521</ref><ref group="xtra">PMID:011888271</ref><references group="xtra"/>
[[Category: Acetylcholinesterase]]
[[Category: Acetylcholinesterase]]
[[Category: Torpedo californica]]
[[Category: Torpedo californica]]

Revision as of 17:46, 20 October 2012

Image:2bag.png

Template:STRUCTURE 2bag

Contents

3D Structure of Torpedo californica acetylcholinesterase complexed with Ganstigmine

Template:ABSTRACT PUBMED 16913695

About this Structure

2bag is a 1 chain structure with sequence from Torpedo californica. Full crystallographic information is available from OCA.

See Also

Reference

  • Bartolucci C, Siotto M, Ghidini E, Amari G, Bolzoni PT, Racchi M, Villetti G, Delcanale M, Lamba D. Structural determinants of Torpedo californica acetylcholinesterase inhibition by the novel and orally active carbamate based anti-alzheimer drug ganstigmine (CHF-2819). J Med Chem. 2006 Aug 24;49(17):5051-8. PMID:16913695 doi:http://dx.doi.org/10.1021/jm060293s
  • Bartolucci C, Perola E, Cellai L, Brufani M, Lamba D. "Back door" opening implied by the crystal structure of a carbamoylated acetylcholinesterase. Biochemistry. 1999 May 4;38(18):5714-9. PMID:10231521 doi:http://dx.doi.org/10.1021/bi982723p
  • Bar-On P, Millard CB, Harel M, Dvir H, Enz A, Sussman JL, Silman I. Kinetic and structural studies on the interaction of cholinesterases with the anti-Alzheimer drug rivastigmine. Biochemistry. 2002 Mar 19;41(11):3555-64. PMID:11888271

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