3hpt
From Proteopedia
(Difference between revisions)
m (Protected "3hpt" [edit=sysop:move=sysop]) |
|||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3hpt]] is a 4 chain structure | + | [[3hpt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HPT OCA]. |
==See Also== | ==See Also== | ||
Revision as of 18:35, 20 October 2012
Contents |
Crystal structure of human FxA in complex with (S)-2-cyano-1-(2-methylbenzofuran-5-yl)-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)guanidine
Template:ABSTRACT PUBMED 19541481
About this Structure
3hpt is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Shi Y, Zhang J, Shi M, O'Connor SP, Bisaha SN, Li C, Sitkoff D, Pudzianowski AT, Chong S, Klei HE, Kish K, Yanchunas J Jr, Liu EC, Hartl KS, Seiler SM, Steinbacher TE, Schumacher WA, Atwal KS, Stein PD. Cyanoguanidine-based lactam derivatives as a novel class of orally bioavailable factor Xa inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4034-41. Epub 2009 Jun 13. PMID:19541481 doi:10.1016/j.bmcl.2009.06.014
Categories: Coagulation factor Xa | Homo sapiens | Ghosh, K. | Kish, K. | Klei, H E. | Rushith, A. | Blood clotting | Blood coagulation | Blood coagulation factor | Cleavage on pair of basic residue | Disulfide bond | Egf-like domain | Epidermal growth factor like domain | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Hydroxylation | Protease | Secreted | Serine protease | Zymogen
