3l58

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==About this Structure==
==About this Structure==
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[[3l58]] is a 2 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L58 OCA].
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[[3l58]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L58 OCA].
==See Also==
==See Also==

Revision as of 18:38, 20 October 2012

Template:STRUCTURE 3l58

Contents

Structure of BACE Bound to SCH589432

Template:ABSTRACT PUBMED 20043696

About this Structure

3l58 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Zhu Z, Sun ZY, Ye Y, Voigt J, Strickland C, Smith EM, Cumming J, Wang L, Wong J, Wang YS, Wyss DF, Chen X, Kuvelkar R, Kennedy ME, Favreau L, Parker E, McKittrick BA, Stamford A, Czarniecki M, Greenlee W, Hunter JC. Discovery of Cyclic Acylguanidines as Highly Potent and Selective beta-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I-Inhibitor Design and Validation ( parallel) (1). J Med Chem. 2010 Feb 11;53(3):951-65. PMID:20043696 doi:10.1021/jm901408p

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