1nmo
From Proteopedia
(New page: 200px<br /><applet load="1nmo" size="450" color="white" frame="true" align="right" spinBox="true" caption="1nmo, resolution 2.20Å" /> '''Structural genomics,...) |
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| - | [[Image:1nmo.jpg|left|200px]]<br /><applet load="1nmo" size=" | + | [[Image:1nmo.jpg|left|200px]]<br /><applet load="1nmo" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1nmo, resolution 2.20Å" /> | caption="1nmo, resolution 2.20Å" /> | ||
'''Structural genomics, protein ybgI, unknown function'''<br /> | '''Structural genomics, protein ybgI, unknown function'''<br /> | ||
==Overview== | ==Overview== | ||
| - | BACKGROUND: The protein encoded by the gene ybgI was chosen as a target | + | BACKGROUND: The protein encoded by the gene ybgI was chosen as a target for a structural genomics project emphasizing the relation of protein structure to function. RESULTS: The structure of the ybgI protein is a toroid composed of six polypeptide chains forming a trimer of dimers. Each polypeptide chain binds two metal ions on the inside of the toroid. CONCLUSION: The toroidal structure is comparable to that of some proteins that are involved in DNA metabolism. The di-nuclear metal site could imply that the specific function of this protein is as a hydrolase-oxidase enzyme. |
==About this Structure== | ==About this Structure== | ||
| - | 1NMO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli,_and_escherichia_coli_o157:h7 Escherichia coli, and escherichia coli o157:h7] with FE as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | + | 1NMO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli,_and_escherichia_coli_o157:h7 Escherichia coli, and escherichia coli o157:h7] with <scene name='pdbligand=FE:'>FE</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NMO OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Escherichia coli, and escherichia coli o157:h7]] | [[Category: Escherichia coli, and escherichia coli o157:h7]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Camerini-Otero, R | + | [[Category: Camerini-Otero, R D.]] |
| - | [[Category: Gilliland, G | + | [[Category: Gilliland, G L.]] |
| - | [[Category: Khil, P | + | [[Category: Khil, P P.]] |
| - | [[Category: Ladner, J | + | [[Category: Ladner, J E.]] |
[[Category: Obmolova, G.]] | [[Category: Obmolova, G.]] | ||
| - | [[Category: S2F, Structure | + | [[Category: S2F, Structure 2.Function Project.]] |
[[Category: Teplyakov, A.]] | [[Category: Teplyakov, A.]] | ||
[[Category: FE]] | [[Category: FE]] | ||
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[[Category: ybgi]] | [[Category: ybgi]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:07:44 2008'' |
Revision as of 12:07, 21 February 2008
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Structural genomics, protein ybgI, unknown function
Overview
BACKGROUND: The protein encoded by the gene ybgI was chosen as a target for a structural genomics project emphasizing the relation of protein structure to function. RESULTS: The structure of the ybgI protein is a toroid composed of six polypeptide chains forming a trimer of dimers. Each polypeptide chain binds two metal ions on the inside of the toroid. CONCLUSION: The toroidal structure is comparable to that of some proteins that are involved in DNA metabolism. The di-nuclear metal site could imply that the specific function of this protein is as a hydrolase-oxidase enzyme.
About this Structure
1NMO is a Single protein structure of sequence from Escherichia coli, and escherichia coli o157:h7 with as ligand. Full crystallographic information is available from OCA.
Reference
Crystal structure of Escherichia coli protein ybgI, a toroidal structure with a dinuclear metal site., Ladner JE, Obmolova G, Teplyakov A, Howard AJ, Khil PP, Camerini-Otero RD, Gilliland GL, BMC Struct Biol. 2003 Sep 30;3:7. PMID:14519207
Page seeded by OCA on Thu Feb 21 14:07:44 2008
Categories: Escherichia coli, and escherichia coli o157:h7 | Single protein | Camerini-Otero, R D. | Gilliland, G L. | Khil, P P. | Ladner, J E. | Obmolova, G. | S2F, Structure 2.Function Project. | Teplyakov, A. | FE | Hypothetical protein | S2f | Structural genomics | Structure 2 function project | Toroidal structure | Ybgi
