3br9
From Proteopedia
(Difference between revisions)
m (Protected "3br9" [edit=sysop:move=sysop]) |
|||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3br9]] is a 2 chain structure | + | [[3br9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BR9 OCA]. |
==See Also== | ==See Also== | ||
Revision as of 19:24, 20 October 2012
Contents |
Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor
Template:ABSTRACT PUBMED 18242088
About this Structure
3br9 is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
See Also
Reference
- Zhou Y, Webber SE, Murphy DE, Li LS, Dragovich PS, Tran CV, Sun Z, Ruebsam F, Shah AM, Tsan M, Showalter RE, Patel R, Li B, Zhao Q, Han Q, Hermann T, Kissinger CR, Lebrun L, Sergeeva MV, Kirkovsky L. Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5- hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1413-8. Epub 2008 Jan 8. PMID:18242088 doi:S0960-894X(08)00010-3
Categories: Hepatitis c virus | RNA-directed RNA polymerase | Han, Q. | Kissinger, C R. | Showalter, R E. | Zhao, Q. | Antiviral | Host-virus interaction | Hydrolase | Metal-binding | Nucleotide-binding | Nucleotidyltransferase | Protein-ligand complex | Ribonucleoprotein | Rna replication | Rna-binding | Rna-directed rna polymerase | Transcription | Transcription regulation | Transferase | Viral nucleoprotein
