3kek
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[3kek]] is a 2 chain structure | + | [[3kek]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEK OCA]. |
==See Also== | ==See Also== | ||
Revision as of 19:37, 20 October 2012
Contents |
Crystal Structure of Human MMP-13 complexed with a (pyridin-4-yl)-2H-tetrazole compound
Template:ABSTRACT PUBMED 20005097
About this Structure
3kek is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Schnute ME, O'Brien PM, Nahra J, Morris M, Howard Roark W, Hanau CE, Ruminski PG, Scholten JA, Fletcher TR, Hamper BC, Carroll JN, Patt WC, Shieh HS, Collins B, Pavlovsky AG, Palmquist KE, Aston KW, Hitchcock J, Rogers MD, McDonald J, Johnson AR, Munie GE, Wittwer AJ, Man CF, Settle SL, Nemirovskiy O, Vickery LE, Agawal A, Dyer RD, Sunyer T. Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis. Bioorg Med Chem Lett. 2010 Jan 15;20(2):576-80. Epub 2009 Nov 22. PMID:20005097 doi:10.1016/j.bmcl.2009.11.081
Categories: Homo sapiens | Collins, B. | Schnute, M E. | Shieh, H S. | Collagen degradation | Disease mutation | Disulfide bond | Extracellular matrix | Glycoprotein | Hydrolase | Hydrolase-hydrolase inhibitor complex | Metal-binding | Metalloprotease | No contact to zn | Protease | S1' inhibitor | S1' specificity | Secreted | Selective mmp-13 inhibitor | Zymogen
