2zm3

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Revision as of 19:50, 20 October 2012

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Template:STRUCTURE 2zm3

Contents 1 Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor 2 About this Structure 3 See Also 4 Reference

Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor

Template:ABSTRACT PUBMED 18501599

About this Structure

2zm3 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Insulin-like growth factor receptor

Reference

• Mayer SC, Banker AL, Boschelli F, Di L, Johnson M, Kenny CH, Krishnamurthy G, Kutterer K, Moy F, Petusky S, Ravi M, Tkach D, Tsou HR, Xu W. Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3641-5. Epub 2008 Apr 25. PMID:18501599 doi:10.1016/j.bmcl.2008.04.044