3juh

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==About this Structure==
==About this Structure==
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[[3juh]] is a 2 chain structure of [[Casein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entries and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ymi 1ymi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUH OCA].
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[[3juh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entries and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ymi 1ymi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUH OCA].
==See Also==
==See Also==

Revision as of 19:57, 20 October 2012

Image:3juh.png

Template:STRUCTURE 3juh

Contents

Crystal structure of a mutant of human protein kinase CK2alpha with altered cosubstrate specificity

Template:ABSTRACT PUBMED 15740749

About this Structure

3juh is a 2 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entries and 1ymi. Full crystallographic information is available from OCA.

See Also

Reference

  • Yde CW, Ermakova I, Issinger OG, Niefind K. Inclining the purine base binding plane in protein kinase CK2 by exchanging the flanking side-chains generates a preference for ATP as a cosubstrate. J Mol Biol. 2005 Mar 25;347(2):399-414. Epub 2005 Jan 18. PMID:15740749 doi:http://dx.doi.org/10.1016/j.jmb.2005.01.003
  • Raaf J, Brunstein E, Issinger OG, Niefind K. The CK2 alpha/CK2 beta interface of human protein kinase CK2 harbors a binding pocket for small molecules. Chem Biol. 2008 Feb;15(2):111-7. PMID:18291315 doi:http://dx.doi.org/10.1016/j.chembiol.2007.12.012
  • Niefind K, Issinger OG. Conformational plasticity of the catalytic subunit of protein kinase CK2 and its consequences for regulation and drug design. Biochim Biophys Acta. 2010 Mar;1804(3):484-92. Epub 2009 Sep 28. PMID:19796713 doi:10.1016/j.bbapap.2009.09.022
  • Niefind K, Raaf J, Issinger OG. Protein kinase CK2 in health and disease: Protein kinase CK2: from structures to insights. Cell Mol Life Sci. 2009 Jun;66(11-12):1800-16. PMID:19387553 doi:10.1007/s00018-009-9149-8

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