2fvd
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
- | [[2fvd]] is a 1 chain structure | + | [[2fvd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FVD OCA]. |
==See Also== | ==See Also== |
Revision as of 20:45, 20 October 2012
Contents |
Cyclin Dependent Kinase 2 (CDK2) with diaminopyrimidine inhibitor
Template:ABSTRACT PUBMED 17064073
About this Structure
2fvd is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Chu XJ, DePinto W, Bartkovitz D, So SS, Vu BT, Packman K, Lukacs C, Ding Q, Jiang N, Wang K, Goelzer P, Yin X, Smith MA, Higgins BX, Chen Y, Xiang Q, Moliterni J, Kaplan G, Graves B, Lovey A, Fotouhi N. Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-diflu oro-6- methoxyphenyl)methanone (R547), a potent and selective cyclin-dependent kinase inhibitor with significant in vivo antitumor activity. J Med Chem. 2006 Nov 2;49(22):6549-60. PMID:17064073 doi:10.1021/jm0606138