1nxi
From Proteopedia
(New page: 200px<br /><applet load="1nxi" size="450" color="white" frame="true" align="right" spinBox="true" caption="1nxi" /> '''Solution structure of Vibrio cholerae protei...) |
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'''Solution structure of Vibrio cholerae protein VC0424'''<br /> | '''Solution structure of Vibrio cholerae protein VC0424'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The structure of Vibrio cholerae protein VC0424 was determined by NMR | + | The structure of Vibrio cholerae protein VC0424 was determined by NMR spectroscopy. VC0424 belongs to a conserved family of bacterial proteins of unknown function (COG 3076). The structure has an alpha-beta sandwich architecture consisting of two layers: a four-stranded antiparallel beta-sheet and three side-by-side alpha-helices. The secondary structure elements have the order alphabetaalphabetabetaalphabeta along the sequence. This fold is the same as the ferredoxin-like fold, except with an additional long N-terminal helix, making it a variation on this common motif. A cluster of conserved surface residues on the beta-sheet side of the protein forms a pocket that may be important for the biological function of this conserved family of proteins. |
==About this Structure== | ==About this Structure== | ||
| - | 1NXI is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http:// | + | 1NXI is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXI OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Vibrio cholerae]] | [[Category: Vibrio cholerae]] | ||
| - | [[Category: Cort, J | + | [[Category: Cort, J R.]] |
[[Category: Goldsmith-Fischman, S.]] | [[Category: Goldsmith-Fischman, S.]] | ||
[[Category: Honig, B.]] | [[Category: Honig, B.]] | ||
| - | [[Category: Kennedy, M | + | [[Category: Kennedy, M A.]] |
| - | [[Category: NESG, Northeast | + | [[Category: NESG, Northeast Structural Genomics Consortium.]] |
[[Category: Ni, S.]] | [[Category: Ni, S.]] | ||
| - | [[Category: Ramelot, T | + | [[Category: Ramelot, T A.]] |
[[Category: ab sandwich]] | [[Category: ab sandwich]] | ||
[[Category: atcc no. 51394d]] | [[Category: atcc no. 51394d]] | ||
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[[Category: structural genomics]] | [[Category: structural genomics]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:11:11 2008'' |
Revision as of 12:11, 21 February 2008
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Solution structure of Vibrio cholerae protein VC0424
Overview
The structure of Vibrio cholerae protein VC0424 was determined by NMR spectroscopy. VC0424 belongs to a conserved family of bacterial proteins of unknown function (COG 3076). The structure has an alpha-beta sandwich architecture consisting of two layers: a four-stranded antiparallel beta-sheet and three side-by-side alpha-helices. The secondary structure elements have the order alphabetaalphabetabetaalphabeta along the sequence. This fold is the same as the ferredoxin-like fold, except with an additional long N-terminal helix, making it a variation on this common motif. A cluster of conserved surface residues on the beta-sheet side of the protein forms a pocket that may be important for the biological function of this conserved family of proteins.
About this Structure
1NXI is a Single protein structure of sequence from Vibrio cholerae. Full crystallographic information is available from OCA.
Reference
Solution structure of Vibrio cholerae protein VC0424: a variation of the ferredoxin-like fold., Ramelot TA, Ni S, Goldsmith-Fischman S, Cort JR, Honig B, Kennedy MA, Protein Sci. 2003 Jul;12(7):1556-61. PMID:12824501
Page seeded by OCA on Thu Feb 21 14:11:11 2008
Categories: Single protein | Vibrio cholerae | Cort, J R. | Goldsmith-Fischman, S. | Honig, B. | Kennedy, M A. | NESG, Northeast Structural Genomics Consortium. | Ni, S. | Ramelot, T A. | Ab sandwich | Atcc no. 51394d | Cog 3076 | Nesg target op3 | Northeast structural genomics consortium | Protein structure initiative | Psi | Structural genomics
